Fibrosis is a condition where tissues stiffen due to the deposition of collagen fibers. As fibrosis progresses, normal organ function deteriorates.
Up to 50,000 × 50,000 pixels can be joined together easily to capture a clear image without stitch lines or brightness variations. Additionally, it is possible to accurately quantify information such as fluorescent signal intensity.
Objective lens: CFI Plan Apo λ 4x Image stitching: 20 images × 12 images
Using the All-in-One Fluorescence Microscope BZ-X800
When a slice of the target is too large to fall within a single field of view, images are captured while moving the stage and a high-resolution image can be created by stitching these images.
Even for tilted specimens or specimens that have height differences, it is possible to create an image in which the entire specimen is in focus. This is accomplished by capturing multiple images in the Z direction and stitching together only the parts that are in focus.
Hybrid Cell Count software can extract only fibrotic areas from the entire section and calculate the proportion automatically.