Quantification of Fibrosis

Automatic batch measurement

Fibrosis of the heart is a phenomenon in which an excess of extracellular collagen accumulates. This phenomenon leads to the hardening of the myocardium, thereby causing a decrease in the performance of the heart.
In recent years, discoveries of factors that prevent fibrosis of the myocardium and research into regenerative medicine and similar areas have been progressing at high speed. Laboratory rats were prepared under various conditions, and then the All-in-One Fluorescence Microscope BZ-X800 was used to quantify the rates of fibrosis.

Objective lens: CFI60 CFI Plan Apo λ 4x
Image stitching: 3 images × 4 images

Batch measurement under the same conditions
Area (total)
57210137 µm2
Area (necrosis)
413032 µm2
Area percentage
0.72%
Batch measurement under the same conditions
Area (total)
75525597 µm2
Area (necrosis)
381812 µm2
Area percentage
0.51%
Batch measurement under the same conditions
Area (total)
77399084 µm2
Area (necrosis)
450871 µm2
Area percentage
0.58%

Using the All-in-One Fluorescence Microscope BZ-X800