High-resolution Imaging of the Periodontal Membrane of Mice

Capturing clear images without fluorescence blurring

The periodontal membrane, also known as periodontal ligament, is a connective tissue that attaches the tooth root to the alveolar bone (upper and lower jawbones).
This fibrous tissue also adjusts bite forces applied to the tooth (impact absorption).

Normal observation
Sectioning observation
Image stitching

Capturing clear images without fluorescence blurring

Objective lens: CFI Plan Apo λ 40x
Image stitching: 5 images × 5 images

Using the All-in-One Fluorescence Microscope BZ-X800

The Sectioning function makes it possible to eliminate fluorescence blurring optically and capture clear images.
A built-in Z-stack function captures multiple images at different focal positions and is able to create a fully focused image by combining only the areas that are at their sharpest focus.
When a slice of the target is too large to fall within a single field of view, images are captured while moving the stage and a high-resolution image can be created by stitching these images.
Each cell can be extracted and counted using Hybrid Cell Count.

Image stitching

Up to 50,000 × 50,000 pixels can be joined together easily to capture a clear image without stitch lines or brightness variations. Additionally, it is possible to accurately quantify information such as fluorescent signal intensity.

Latest Fluorescence Microscope Catalog

BZ-X Series All-in-One Fluorescence Microscope Catalog — Check out the catalog on KEYENCE’s newest All-in-One Fluorescence Microscope BZ-X800.

Get the catalog for more details

For More Information

BZ-X800 All-in-One Fluorescence Microscope: Application Guide Vol.4 — Materials on various applications in different areas are also available.

Download materials

Fluorescence Microscopes Product Lineup

Here are some examples of using the All-in-One Fluorescence Microscope BZ-X800 in front-line research.: [Myelodysplastic Syndromes (MDS)] Stitching, Sectioning and the Z-Stack Function as Decisive Arguments for the Acquisition of the BZ Fluorescence Microscope at the University Hospital of Düsseldorf; [Neuropathology] The perfect solution for everyday patient diagnostics and clinical research at the Institute of Neuropathology in the Charité hospital in Berlin; [Regenerative Medicine] BZ Series Provides Essential Imaging for Neural Stem Cell and Spinal Observation; [Gene Therapy] Improving Research for the Development of Gene Therapy Drugs; [Heart Disease Treatment] Developing Cell Sheets for Myocardial Regenerative Treatments; [Cancer Treatment] Automated Fluorescence Microscope Transforms Process for Induced Cancer Stem Cell Research; [Immune System] BZ Series Contributes to Understanding the Pathological Model of Asthma; [Biomaterials] Promoting Efficiency in Research With Compact, User-friendly Microscopes

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