High-resolution Imaging of the Periodontal Membrane of Mice
Capturing clear images without fluorescence blurring
The periodontal membrane, also known as periodontal ligament, is a connective tissue that attaches the tooth root to the alveolar bone (upper and lower jawbones).
This fibrous tissue also adjusts bite forces applied to the tooth (impact absorption).
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Normal observation
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Sectioning observation
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Image stitching

Objective lens: CFI Plan Apo λ 40x
Image stitching: 5 images × 5 images
Using the All-in-One Fluorescence Microscope BZ-X800
- The Sectioning function makes it possible to eliminate fluorescence blurring optically and capture clear images.
- A built-in Z-stack function captures multiple images at different focal positions and is able to create a fully focused image by combining only the areas that are at their sharpest focus.
- When a slice of the target is too large to fall within a single field of view, images are captured while moving the stage and a high-resolution image can be created by stitching these images.
- Each cell can be extracted and counted using Hybrid Cell Count.
Image stitching
Up to 50,000 × 50,000 pixels can be joined together easily to capture a clear image without stitch lines or brightness variations. Additionally, it is possible to accurately quantify information such as fluorescent signal intensity.
- Here are some examples of using the All-in-One Fluorescence Microscope BZ-X800 in front-line research.
- [Regenerative Medicine] BZ Series Provides Essential Imaging for Neural Stem Cell and Spinal Observation
- [Gene Therapy] Improving Research for the Development of Gene Therapy Drugs
- [Heart Disease Treatment] Developing Cell Sheets for Myocardial Regenerative Treatments
- [Cancer Treatment] Automated Fluorescence Microscope Transforms Process for Induced Cancer Stem Cell Research
- [Immune System] BZ Series Contributes to Understanding the Pathological Model of Asthma
- [Biomaterials] Promoting Efficiency in Research With Compact, User-friendly Microscopes